TLR7 Signaling Drives the Development of Sjögren’s Syndrome

Sjögren’s syndrome (SS) is a chronic systemic autoimmune disease that affects predominately salivary and lacrimal glands. SS can occur alone or in combination with another autoimmune disease like systemic lupus erythematosus (SLE). Here we report that TLR7 signaling drives the development of SS sinc...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Yawen Wang, Annie Roussel-Queval, Lionel Chasson, Noël Hanna Kazazian, Laetitia Marcadet, Andrianos Nezos, Michael H. Sieweke, Clio Mavragani, Lena Alexopoulou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Subjects:
Sjögren’s syndrome (SS)
TLR7
innate immunity
autoimmunity
TLR8-deficient mice
dendritic cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.676010/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.676010/full

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