Clorfl86/RHEX Is a Negative Regulator of SCF/KIT Signaling in Human Skin Mast Cells

Mast cells (MCs) are key effector cells in allergic and inflammatory diseases, and the SCF/KIT axis regulates most aspects of the cells’ biology. Using terminally differentiated skin MCs, we recently reported on proteome-wide phosphorylation changes initiated by KIT dimerization. C1orf186/RHEX was r...

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Bibliographic Details
Published in:Cells
Main Authors: Kristin Franke, Gürkan Bal, Zhuoran Li, Torsten Zuberbier, Magda Babina
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Subjects:
mast cell
RHEX
C1orf186
survival
apoptosis
signal transduction
Online Access:https://www.mdpi.com/2073-4409/12/9/1306

Internet

https://www.mdpi.com/2073-4409/12/9/1306

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