Detection and characterization of pancreatic and biliary tract cancers using cell-free DNA fragmentomics

Abstract Background Plasma cell-free DNA (cfDNA) fragmentomics has demonstrated significant differentiation power between cancer patients and healthy individuals, but little is known in pancreatic and biliary tract cancers. The aim of this study is to characterize the cfDNA fragmentomics in biliopan...

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Bibliographic Details

Published in:	Journal of Experimental & Clinical Cancer Research
Main Authors:	Xiaohan Shi, Shiwei Guo, Qiaonan Duan, Wei Zhang, Suizhi Gao, Wei Jing, Guojuan Jiang, Xiangyu Kong, Penghao Li, Yikai Li, Chuanqi Teng, Xiaoya Xu, Sheng Chen, Baoning Nian, Zhikuan Li, Chaoliang Zhong, Xiaolu Yang, Guangyu Zhu, Yiqi Du, Dadong Zhang, Gang Jin
Format:	Article
Language:	English
Published:	BMC 2024-05-01
Subjects:	Biliopancreatic cancer Cell-free DNA Fragmentomics Low-coverage whole-genome sequencing
Online Access:	https://doi.org/10.1186/s13046-024-03067-y