Melatonin Inhibits Formation of Mitochondrial Permeability Transition Pores and Improves Oxidative Phosphorylation of Frozen-Thawed Ram Sperm

Structural and functional damages to mitochondria of frozen-thawed sperm are a typical cryoinjury, with mitochondrial permeability transition pore (MPTP) formation being the hallmark change. Mitochondria are both a primary synthesis site and principle target for melatonin; this compound can directly...

Full description

Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Yi Fang, Chengzhen Zhao, Hai Xiang, Xueli Zhao, Rongzhen Zhong
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-01-01
Subjects:	ram sperm cryopreservation melatonin mitochondrial permeability transition pore oxidative phosphorylation
Online Access:	https://www.frontiersin.org/article/10.3389/fendo.2019.00896/full