SMURF1 facilitates estrogen receptor ɑ signaling in breast cancer cells

Abstract Background Estrogen receptor alpha (ER alpha) is expressed in the majority of breast cancers and promotes estrogen-dependent cancer progression. ER alpha positive breast cancer can be well controlled by ER alpha modulators, such as tamoxifen. However, tamoxifen resistance is commonly observ...

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Bibliographic Details

Published in:	Journal of Experimental & Clinical Cancer Research
Main Authors:	Huijie Yang, Na Yu, Juntao Xu, Xiaosheng Ding, Wei Deng, Guojin Wu, Xin Li, Yingxiang Hou, Zhenhua Liu, Yan Zhao, Min Xue, Sifan Yu, Beibei Wang, Xiumin Li, Gang Niu, Hui Wang, Jian Zhu, Ting Zhuang
Format:	Article
Language:	English
Published:	BMC 2018-02-01
Subjects:	SMURF1 ER alpha Breast cancer Ubiquitination Protein stability
Online Access:	http://link.springer.com/article/10.1186/s13046-018-0672-z