A kernelisation approach for multiple d-Hitting Set and its application in optimal multi-drug therapeutic combinations.

Therapies consisting of a combination of agents are an attractive proposition, especially in the context of diseases such as cancer, which can manifest with a variety of tumor types in a single case. However uncovering usable drug combinations is expensive both financially and temporally. By employi...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Drew Mellor, Elena Prieto, Luke Mathieson, Pablo Moscato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20976188/?tool=EBI