The Ubiquitin Ligase SIAH2 Negatively Regulates Glucocorticoid Receptor Activity and Abundance

Glucocorticoids are clinically essential drugs used routinely to control inflammation. However, a host of metabolic side effects manifests upon usage beyond a few days. In the present study, we tested the hypothesis that seven-in-absentia mammalian homolog-2 (SIAH2), a ubiquitin ligase that regulate...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Susan J. Burke, Jessica L. Taylor, Heidi M. Batdorf, Robert C. Noland, David H. Burk, Yongmei Yu, Z. Elizabeth Floyd, J. Jason Collier
Format:	Article
Language:	English
Published:	MDPI AG 2020-12-01
Subjects:	adipose tissue glucocorticoid inflammation SIAH2
Online Access:	https://www.mdpi.com/2227-9059/9/1/22