Antimicrobial Activity of Non-steroidal Anti-inflammatory Drugs on Biofilm: Current Evidence and Potential for Drug Repurposing

It has been demonstrated that some non-steroidal anti-inflammatory drugs (NSAIDs), like acetylsalicylic acid, diclofenac, and ibuprofen, have anti-biofilm activity in concentrations found in human pharmacokinetic studies, which could fuel an interest in repurposing these well tolerated drugs as adju...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Rodrigo Cuiabano Paes Leme, Raquel Bandeira da Silva
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-07-01
Subjects:	non-steroidal anti-inflammatory drugs biofilm Staphylococcus aureus gram-negative pathogens antibiotic resistance
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.707629/full