Fidgetin-like1 is a strong candidate for a dynamic impairment of male meiosis leading to reduced testis weight in mice.

BACKGROUND: In a previous work, using an interspecific recombinant congenic mouse model, we reported a genomic region of 23 Mb on mouse chromosome 11 implicated in testis weight decrease and moderate teratozoospermia (∼20-30%), a Quantitative Trait Locus (QTL) called Ltw1. The objective of the prese...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	David L'Hôte, Magalie Vatin, Jana Auer, Johan Castille, Bruno Passet, Xavier Montagutelli, Catherine Serres, Daniel Vaiman
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Online Access:	http://europepmc.org/articles/PMC3217987?pdf=render