bb0689 contributes to the virulence of Borrelia burgdorferi in a murine model of Lyme disease

ABSTRACT Borrelia burgdorferi, the Lyme disease pathogen, continuously changes its gene expression profile in order to adapt to ticks and mammalian hosts. The alternative sigma factor RpoS plays a central role in borrelial host adaptation. Global transcriptome analyses suggested that more than 100 g...

Full description

Bibliographic Details

Published in:	Infection and Immunity
Main Authors:	Connor Waldron, Sierra George, Christina Thompson, Yu Hsien Liao, Zhiming Ouyang
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-01-01
Subjects:	Lyme disease Borrelia burgdorferi RpoS virulence regulation gene regulation pathogenesis
Online Access:	https://journals.asm.org/doi/10.1128/iai.00459-24