Imputation provides an opportunity to study filaggrin (FLG) null mutations in large population cohorts that lack bespoke genotyping [version 2; peer review: 2 approved]
Background Null mutations within the filaggrin (FLG) gene are established genetic risk factors for atopic dermatitis. Studies of FLG have typically used sequencing or bespoke genotyping. Large-scale population cohorts with genome-wide imputed data offer powerful genetic analysis opportunities, but b...
| Published in: | Wellcome Open Research |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Wellcome
2024-05-01
|
| Subjects: | |
| Online Access: | https://wellcomeopenresearch.org/articles/7-36/v2 |