Urokinase-Type Plasminogen Activator System in Norm and in Life-Threatening Processes (Review)

The multifunctional urokinase-type plasminogen activator system (uPA-system) includes serine proteinase — uPA or urokinase, its receptor (uPAR) and two inhibitors (PAI-1 and PAI-2). The review discusses the structural features and involvement of the system components in the development of life-threa...

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Bibliographic Details

Published in:	Общая реаниматология
Main Authors:	Elena V. Kugaevskaya, Tatiana A. Gureeva, Olga S. Timoshenko, Nina I. Solovyeva
Format:	Article
Language:	English
Published:	Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2018-12-01
Subjects:	upa upar pai-1 pai-2 matrix metalloproteinases carcinogenesis inflammation neurogenesis fibrinolysis
Online Access:	https://www.reanimatology.com/rmt/article/view/1726