OLD family nuclease function across diverse anti-phage defense systems

Bacteriophages constitute a ubiquitous threat to bacteria, and bacteria have evolved numerous anti-phage defense systems to protect themselves. These systems include well-studied phenomena such as restriction endonucleases and CRISPR, while emerging studies have identified many new anti-phage defens...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Konstantina Akritidou, Bryan H. Thurtle-Schmidt
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-09-01
Subjects:	OLD nuclease overcoming lysogenization defect Gabija retrons Toprim ABC ATPase
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2023.1268820/full