Splice site m6A methylation prevents binding of DGCR8 to suppress KRT4 pre-mRNA splicing in oral squamous cell carcinoma

Oral squamous cell carcinoma (OSCC) is the 11th most prevalent tumor worldwide. Despite advantages of therapeutic approaches, the 5-year survival rate of patients with OSCC is less than 50%. It is urgent to elucidate mechanisms underlying OSCC progression for developing novel treatment strategies. O...

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Bibliographic Details

Published in:	PeerJ
Main Authors:	Xiaoxu Li, Juan Fang, Xiaoan Tao, Juan Xia, Bin Cheng, Yun Wang
Format:	Article
Language:	English
Published:	PeerJ Inc. 2023-02-01
Subjects:	Oral squamous cell carcinoma Keratin 4 m6A methylation Pre-mRNA splicing
Online Access:	https://peerj.com/articles/14824.pdf