Mutations primarily alter the inclusion of alternatively spliced exons
Genetic analyses and systematic mutagenesis have revealed that synonymous, non-synonymous and intronic mutations frequently alter the inclusion levels of alternatively spliced exons, consistent with the concept that altered splicing might be a common mechanism by which mutations cause disease. Howev...
| 發表在: | eLife |
|---|---|
| Main Authors: | , , , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
eLife Sciences Publications Ltd
2020-10-01
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| 主題: | |
| 在線閱讀: | https://elifesciences.org/articles/59959 |