Increased cardiac myosin super-relaxation as an energy saving mechanism in hibernating grizzly bears

Aim: The aim of the present study was to define whether cardiac myosin contributes to energy conservation in the heart of hibernating mammals. Methods: Thin cardiac strips were isolated from the left ventricles of active and hibernating grizzly bears; and subjected to loaded Mant-ATP chase assays, X...

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Bibliographic Details

Published in:	Molecular Metabolism
Main Authors:	Robbert J. Van der Pijl, Weikang Ma, Christopher T.A. Lewis, Line Haar, Amalie Buhl, Gerrie P. Farman, Marcus Rhodehamel, Vivek P. Jani, O Lynne Nelson, Chengxin Zhang, Henk Granzier, Julien Ochala
Format:	Article
Language:	English
Published:	Elsevier 2025-02-01
Subjects:	Hibernation Heart Myosin Metabolism
Online Access:	http://www.sciencedirect.com/science/article/pii/S2212877824002151