Maintenance therapy for <i>FLT3-ITD</i>-mutated acute myeloid leukemia
FLT3-ITD is a constitutively activated variant of the FLT3 tyrosine kinase receptor. Its expression in acute myeloid leukemia (AML) is associated with a poor prognosis. Due to this, the development of tyrosine kinase inhibitors (TKI) blocking FLT3-ITD became a rational therapeutic concept. This rev...
| Published in: | Haematologica |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Ferrata Storti Foundation
2021-01-01
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| Online Access: | https://haematologica.org/article/view/10147 |