Corticotropin-releasing hormone inhibits autophagy by suppressing PTEN to promote apoptosis in dermal papilla cells

Background Stress-related hair loss is on the rise, largely due to escalating levels of stress-related corticotropin-releasing hormone (CRH) through poorly defined mechanisms. CRH-mediated activation of corticotropin-releasing hormone receptors (CRHRs) on dermal papilla cells (DPCs) is a likely caus...

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Bibliographic Details

Published in:	Annals of Medicine
Main Authors:	Wenzi Liang, Xiuwen Chen, Na Ni, Chutong Zhuang, Zhiying Yu, Ziqing Xu, Yingshi Li, Changmin Lin, Keng Huang
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Subjects:	Hair loss hair regrowth chronic unpredictable mild stress PI3K/AKT/mTOR hypothalamic–pituitary–adrenal axis
Online Access:	https://www.tandfonline.com/doi/10.1080/07853890.2025.2490823