Patient-derived organoid elucidates the identical clonal origin of bilateral breast cancer with diverse molecular subtypes

Bilateral breast cancer (BBC), an infrequent breast cancer subtype, has primarily been studied in terms of incidence, prognosis, and through comparative analysis of synchronous (SBBC) and metachronous (MBBC) manifestations. The advent and application of organoid technology hold profound implications...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Zhongbin Han, Liangxue Yao, Yanhua Fang, Sijing Chen, Ruiqing Lian, Yongqiang Yao, Hongsheng Chen, Xuening Ji, Weiting Yu, Zhe Wang, Ruoyu Wang, Shanshan Liang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-05-01
Subjects:	organoids bilateral breast cancer driver mutations evolution molecular subtypes
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1361603/full