Visible-light-induced nickel-catalyzed α-hydroxytrifluoroethylation of alkyl carboxylic acids: Access to trifluoromethyl alkyl acyloins

A visible-light-induced nickel-catalyzed cross coupling of alkyl carboxylic acids with N-trifluoroethoxyphthalimide is described. Under purple light irradiation, an α-hydroxytrifluoroethyl radical generated from a photoactive electron donor–acceptor complex between Hantzsch ester and N-trifluoroetho...

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Bibliographic Details

Published in:	Beilstein Journal of Organic Chemistry
Main Authors:	Feng Chen, Xiu-Hua Xu, Zeng-Hao Chen, Yue Chen, Feng-Ling Qing
Format:	Article
Language:	English
Published:	Beilstein-Institut 2023-09-01
Subjects:	alkyl carboxylic acids cross coupling eda complex nickel catalysis trifluoromethyl acyloins
Online Access:	https://doi.org/10.3762/bjoc.19.98