A Ru(II)-Strained Complex with 2,9-Diphenyl-1,10-phenanthroline Ligand Induces Selective Photoactivatable Chemotherapeutic Activity on Human Alveolar Carcinoma Cells via Apoptosis

[Ru(bipy)<sub>2</sub>(dpphen)]Cl<sub>2</sub> (where bipy = 2,2′-bipyridine and dpphen = 2,9-diphenyl-1,10-phenanthroline) (complex <b>1</b>) is a sterically strained compound that exhibits promising in vitro photocytotoxicity on an array of cell lines. Since lung...

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Bibliographic Details
Published in:Pharmaceuticals
Main Authors: Najwa Mansour, Stephanie Mehanna, Kikki Bodman-Smith, Costantine F. Daher, Rony S. Khnayzer
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Subjects:
ruthenium
anticancer
A549
photoactivatable chemotherapy
in vitro photochemotherapy
Online Access:https://www.mdpi.com/1424-8247/17/1/50

Internet

https://www.mdpi.com/1424-8247/17/1/50

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