Loss of ADAMTS5 enhances brown adipose tissue mass and promotes browning of white adipose tissue via CREB signaling

Objective: A potential strategy to treat obesity – and the associated metabolic consequences – is to increase energy expenditure. This could be achieved by stimulating thermogenesis through activation of brown adipose tissue (BAT) and/or the induction of browning of white adipose tissue (WAT). Over...

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Bibliographic Details

Published in:	Molecular Metabolism
Main Authors:	Dries Bauters, Mathias Cobbaut, Lotte Geys, Johan Van Lint, Bianca Hemmeryckx, H. Roger Lijnen
Format:	Article
Language:	English
Published:	Elsevier 2017-07-01
Subjects:	ADAMTS5 Brown adipose tissue Browning Beige Thermogenesis Obesity
Online Access:	http://www.sciencedirect.com/science/article/pii/S2212877817302818