CX691 as an AMPA receptor positive modulator, improves the learning and memory in a rat model of Alzheimer’s disease

Objective(s): Growing evidence suggests that dysfunction of the glutamatergic system and α-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid (AMPA) receptors are involved in pathology of Alzheimer’s disease (AD). Because AMPA receptors play a key role in plasticity synaptic regulation, positive modu...

Full description

Bibliographic Details

Published in:	Iranian Journal of Basic Medical Sciences
Main Authors:	Nazanin Mozafari, Ali Shamsizadeh, Iman Fatemi, Mohammad Allahtavakoli, Amir Moghadam-Ahmadi, Elham Kaviani, Ayat Kaeidi
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2018-07-01
Subjects:	Alzheimer’s disease AMPA receptors BDNF CX691 Memory Rat
Online Access:	http://ijbms.mums.ac.ir/article_10760_8bdeb1455cbdce80a0dc8c5f31b64d8e.pdf