Validation and Optimization of an Image-Based Screening Method Applied to the Study of Neuronal Processes on Nanogrooves

Research on neuronal differentiation and neuronal network guidance induced through nanotopographical cues generates large datasets, and therefore the analysis of such data can be aided by automatable, unbiased image screening tools. To link such tools, we present an image-based screening method to e...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Alex J. Bastiaens, Sijia Xie, Dana A. M. Mustafa, Jean-Philippe Frimat, Jaap M. J. den Toonder, Regina Luttge
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-11-01
Subjects:	SH-SY5Y cells nanogrooves neuronal differentiation neuronal development neurite development high-content screening
Online Access:	https://www.frontiersin.org/article/10.3389/fncel.2018.00415/full