Comparison evaluation of bacterial DNA extraction methods for improved molecular diagnostic accuracy of sepsis-causing pathogens in clinical whole blood samples

Abstract Sepsis, a leading cause of mortality, requires rapid and accurate pathogen identification to ensure effective treatment. Current diagnostic methods such as blood cultures are time-consuming, whereas molecular diagnostic techniques represent a promising alternative for faster pathogen detect...

Full description

Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Byungjoon Na, Junghun Park, Sojin Park, Eunseon Park, Jimin Jang, Yu-Hee Kim, Jinyeop Lee, Hae-Sun Chung
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-02-01
Subjects:	Sepsis DNA extraction Molecular diagnostic technique Magnetic bead Whole blood
Online Access:	https://doi.org/10.1038/s41598-025-87225-y