SIRT1 Protects the Heart from ER Stress-Induced Injury by Promoting eEF2K/eEF2-Dependent Autophagy

Many recent studies have demonstrated the involvement of endoplasmic reticulum (ER) stress in the development of cardiac diseases and have suggested that modulation of ER stress response could be cardioprotective. Previously, we demonstrated that the deacetylase Sirtuin 1 (SIRT1) attenuates ER stres...

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Bibliographic Details

Published in:	Cells
Main Authors:	Julie Pires Da Silva, Kevin Monceaux, Arnaud Guilbert, Mélanie Gressette, Jérôme Piquereau, Marta Novotova, Renée Ventura-Clapier, Anne Garnier, Christophe Lemaire
Format:	Article
Language:	English
Published:	MDPI AG 2020-02-01
Subjects:	sirtuin 1 endoplasmic reticulum stress autophagy/mitophagy cell death cardioprotection
Online Access:	https://www.mdpi.com/2073-4409/9/2/426