KIR/HLA pleiotropism: protection against both HIV and opportunistic infections.

The compound genotype KIR3DS1/HLA-B Bw4-80I, which presumably favors natural killer cell activation, has been implicated in protection against HIV disease. We show that this genotype confers dual protection over the course of HIV disease; early direct containment of HIV viral load, and late specific...

Full description

Bibliographic Details
Published in:PLoS Pathogens
Main Authors: Ying Qi, Maureen P Martin, Xiaojiang Gao, Lisa Jacobson, James J Goedert, Susan Buchbinder, Gregory D Kirk, Stephen J O'Brien, John Trowsdale, Mary Carrington
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-08-01
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.0020079&type=printable

Internet

https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.0020079&type=printable

Similar Items