KIR/HLA pleiotropism: protection against both HIV and opportunistic infections.

The compound genotype KIR3DS1/HLA-B Bw4-80I, which presumably favors natural killer cell activation, has been implicated in protection against HIV disease. We show that this genotype confers dual protection over the course of HIV disease; early direct containment of HIV viral load, and late specific...

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Bibliographic Details
Published in:	PLoS Pathogens
Main Authors:	Ying Qi, Maureen P Martin, Xiaojiang Gao, Lisa Jacobson, James J Goedert, Susan Buchbinder, Gregory D Kirk, Stephen J O'Brien, John Trowsdale, Mary Carrington
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2006-08-01
Online Access:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.0020079&type=printable

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