gcMECM: graph clustering of mutual exclusivity of cancer mutations

Abstract Background Next-generation sequencing platforms allow us to sequence millions of small fragments of DNA simultaneously, revolutionizing cancer research. Sequence analysis has revealed that cancer driver genes operate across multiple intricate pathways and networks with mutations often occur...

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Bibliographic Details

Published in:	BMC Bioinformatics
Main Authors:	Ying Hu, Chunhua Yan, Qingrong Chen, Daoud Meerzaman
Format:	Article
Language:	English
Published:	BMC 2021-12-01
Subjects:	Cancer driver genes Mutually exclusive mutations Network analysis R package
Online Access:	https://doi.org/10.1186/s12859-021-04505-w