Loss of Human Beta Cell Identity in a Reconstructed Omental Stromal Cell Environment

In human type 2 diabetes, adipose tissue plays an important role in disturbing glucose homeostasis by secreting factors that affect the function of cells and tissues throughout the body, including insulin-producing pancreatic beta cells. We aimed here at studying the paracrine effect of stromal cell...

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Bibliographic Details
Published in:Cells
Main Authors: Blandine Secco, Kevin Saitoski, Karima Drareni, Antoine Soprani, Severine Pechberty, Latif Rachdi, Nicolas Venteclef, Raphaël Scharfmann
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Subjects:
EndoC-βH1
dedifferentiation
stromal cells
type 2 diabetes
adipose tissue
human pancreatic beta cells
Online Access:https://www.mdpi.com/2073-4409/11/6/924

Internet

https://www.mdpi.com/2073-4409/11/6/924

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