Efficient micro-recovery and guanidination of peptides directly from MALDI target spots

A method is presented for the recovery and subsequent guanidination of tryptic peptides from samples previously spotted on a matrix-assisted laser desorption/ionization (MALDI) target. The procedure is shown to have applicability to both in-solution and in-gel digests, yielding improved confidence i...

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Bibliographic Details

Published in:	BioTechniques
Main Authors:	Steven L. Cockrill, Kelly L. Foster, Justin Wildsmith, April R. Goodrich, John G. Dapron, Tom C. Hassell, William K. Kappel, Graham B.I. Scott
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2005-02-01
Online Access:	https://www.future-science.com/doi/10.2144/05382PT02