Regulation of replication timing in Saccharomyces cerevisiae.

In order to maintain genomic integrity, DNA replication must be highly coordinated. Disruptions in this process can cause replication stress which is aberrant in many pathologies including cancer. Despite this, little is known about the mechanisms governing the temporal regulation of DNA replication...

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Bibliographic Details
Published in:PLoS Computational Biology
Main Authors: Rosie Berners-Lee, Eamonn Gilmore, Francisco Berkemeier, Michael A Boemo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Online Access:https://doi.org/10.1371/journal.pcbi.1013066