Toll-like Receptor 4 Is Upregulated in Parkinson’s Disease Patients and Co-Localizes with pSer129αSyn: A Possible Link with the Pathology

Growing evidence suggests a crucial role of neuroinflammation in the pathophysiology of Parkinson’s disease (PD). Neuroinflammation is linked to the accumulation and aggregation of a-synuclein (αSyn), the primary pathological hallmark of PD. Toll-like receptors 4 (TLR4) can have implications in the...

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Bibliographic Details

Published in:	Cells
Main Authors:	Carmela Conte, Angela Ingrassia, John Breve, John J. Bol, Evelien Timmermans-Huisman, Anne-Marie van Dam, Tommaso Beccari, Wilma D. J. van de Berg
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Subjects:	Parkinson’s disease neuroinflammation alpha-synuclein substantia nigra pars compacta middle temporal gyrus
Online Access:	https://www.mdpi.com/2073-4409/12/10/1368