Therapy-induced senescent tumor cells in cancer relapse

Cellular senescence is characterized by a generally irreversible cell cycle arrest and the secretion of bioactive factors known as the senescence-associated secretory phenotype (SASP). In an oncogenic context, senescence is considered a tumor suppressive mechanism as it prevents cell proliferation a...

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Bibliographic Details

Published in:	Journal of the National Cancer Center
Main Authors:	Ke-Xin Song, Jun-Xian Wang, De Huang
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Subjects:	Cancer therapy Tumor cell senescence Relapse
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667005423000649