RIG-I ATPase Activity and Discrimination of Self-RNA versus Non-Self-RNA

ABSTRACT Many RNA viruses are detected by retinoic acid-inducible gene i (RIG-I), a cytoplasmic sensor that triggers an antiviral response upon binding non-self-RNA that contains a stretch of double-stranded RNA (dsRNA) bearing a base-paired 5′ ppp nucleotide. To gain insight into how RIG-I discrimi...

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Bibliographic Details

Published in:	mBio
Main Authors:	Stéphanie Anchisi, Jessica Guerra, Dominique Garcin
Format:	Article
Language:	English
Published:	American Society for Microbiology 2015-05-01
Online Access:	https://journals.asm.org/doi/10.1128/mBio.02349-14