PEGylated Mesoporous Silica Nanoparticles (MCM-41): A Promising Carrier for the Targeted Delivery of Fenbendazole into Prostrate Cancer Cells

Low water solubility and thus low bioavailability limit the clinical application of fenbendazole (FBZ) as a potential anticancer drug. Solubilizing agents, such as Mobil Composition of Matter Number 41 (MCM) as a drug carrier, can improve the water solubility of drugs. In this study, PEGylated MCM (...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Maedeh Koohi Moftakhari Esfahani, Seyed Ebrahim Alavi, Peter J. Cabot, Nazrul Islam, Emad L. Izake
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Subjects:	drug delivery systems drug repurposing MCM-41 mesoporous silica nanoparticle solubility
Online Access:	https://www.mdpi.com/1999-4923/13/10/1605