A multifunctional scaffold that promotes the scaffold-tissue interface integration and rescues the ROS microenvironment for repair of annulus fibrosus defects

Due to the limited self-repair ability of the annulus fibrosus (AF), current tissue engineering strategies tend to use structurally biomimetic scaffolds for AF defect repair. However, the poor integration between implanted scaffolds and tissue severely affects their therapeutic effects. To solve thi...

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Bibliographic Details

Published in:	Bioactive Materials
Main Authors:	Runze Zhao, Feng Han, Qifan Yu, Zhuang Zhu, Zhengdong Tu, Tingting Xia, Bin Li
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2024-11-01
Subjects:	Annulus fibrosus Scaffold-tissue integration Lysyl oxidase Reactive oxygen species regulation Manganese dioxide nanoparticles
Online Access:	http://www.sciencedirect.com/science/article/pii/S2452199X24000884