Characterization of AAV vectors: A review of analytical techniques and critical quality attributes

Standardized evaluation of adeno-associated virus (AAV) vector products for biotherapeutic application is essential to ensure the safety and efficacy of gene therapies. This includes analyzing the critical quality attributes of the product. However, many of the current analytical techniques used to...

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Bibliographic Details

Published in:	Molecular Therapy: Methods & Clinical Development
Main Authors:	Theodoros Kontogiannis, Julian Braybrook, Christopher McElroy, Carole Foy, Alexandra S. Whale, Milena Quaglia, C Mark Smales
Format:	Article
Language:	English
Published:	Elsevier 2024-09-01
Subjects:	AAV viral vector critical quality attributes CQAs gene therapy analytical methodologies
Online Access:	http://www.sciencedirect.com/science/article/pii/S2329050124001256