Pyrrolizine- and Indolizine-Derived Spirooxindoles: Synthesis, Antibacterial Activity and Inverse Docking Analysis

Spirooxindoles are a family of heterocyclic compounds which bear the oxindole nucleus in their structures, which have a considerable pharmaceutical potential and which have been linked to various drugs for the treatment of diverse diseases. In this work, a wide variety of spirooxindoles bearing a py...

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Bibliographic Details

Published in:	Chemistry
Main Authors:	Pablo Romo, María del Pilar Crespo, Mauricio Barreto, María Elena Burbano, Melissa Mejia-Gutierrez, Jairo Quiroga, Rodrigo Abonia
Format:	Article
Language:	English
Published:	MDPI AG 2025-02-01
Subjects:	spirooxindoles 1,3-dipolar cycloaddition isatin antibacterial activity inverse docking analysis
Online Access:	https://www.mdpi.com/2624-8549/7/1/18