Utilizing hiPSC-derived oligodendrocytes to study myelin pathophysiology in neuropsychiatric and neurodegenerative disorders.

Oligodendrocytes play a crucial role in our central nervous system (CNS) by myelinating axons for faster action potential conduction, protecting axons from degeneration, structuring the position of ion channels, and providing nutrients to neurons. Oligodendrocyte dysfunction and/or dysmyelination ca...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Gina Shim, Alejandra I. Romero-Morales, Srinidhi R. Sripathy, Brady J. Maher
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-01-01
Subjects:	oligodendrocytes stem cells myelination neuropsychiatric disease neurodegenerative disease neural organoids
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2023.1322813/full