Identification of tauopathy-associated lipid signatures in Alzheimer’s disease mouse brain using label-free chemical imaging

Abstract There is cumulative evidence that lipid metabolism plays a key role in the pathogenesis of various neurodegenerative disorders including Alzheimer’s disease (AD). Visualising lipid content in a non-destructive label-free manner can aid in elucidating the AD phenotypes towards a better under...

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Bibliographic Details

Published in:	Communications Biology
Main Authors:	Hao Meng, Alicia Elliott, Jessica Mansfield, Michelle Bailey, Mark Frogley, Gianfelice Cinque, Julian Moger, Nick Stone, Francesco Tamagnini, Francesca Palombo
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-10-01
Online Access:	https://doi.org/10.1038/s42003-024-07034-3