RORα fine-tunes the circadian control of hepatic triglyceride synthesis and gluconeogenesis

Abstract Circadian rhythms play a fundamental role in hepatic metabolism, orchestrating lipid synthesis and glucose homeostasis. RORα, a nuclear receptor involved in circadian regulation, has been implicated in fine-tuning these metabolic processes. We previously showed a therapeutic potential of an...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Chloé Monnier, Munkhzul Ganbold, Martine Auclair, Natacha Roblot, Andréas Barnabé Boutin, Paul Ketil Boutin, Bruno Fève, Bénédicte Antoine
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-03-01
Subjects:	Liver Lipid synthesis RORα Circadian rhythms Gluconeogenesis Staggerer
Online Access:	https://doi.org/10.1038/s41598-025-95228-y