Pericranial Muscle Stiffness, Pain Thresholds, and Tenderness during a Treatment Cycle of OnabotulinumtoxinA for Chronic Migraine Prevention

Background: Treatment with OnabotulinumtoxinA (BoNT-A) is effective as a preventive treatment for chronic migraine (CM). Preclinical studies suggest that the mechanism of action of BoNT-A in migraine is based on blocking unmyelinated C fibers. We aimed to investigate whether the muscle-relaxing effe...

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Bibliographic Details
Published in:Diagnostics
Main Authors: Sebastian Worsaae Dalby, Jeppe Hvedstrup, Louise Ninett Carlsen, Sait Ashina, Lars Bendtsen, Henrik Winther Schytz
Format: Article
Language:English
Published: MDPI AG 2024-02-01
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Online Access:https://www.mdpi.com/2075-4418/14/3/330