Pyrazolopyridine pyrimidone hybrids as potential DprE1 inhibitors, design, synthesis and biological evaluation as antitubercular agents
Abstract Tuberculosis (TB) remains a major global health challenge. This study presents the design, synthesis, and evaluation of some novel pyrazolo[3,4-b]pyridine-pyrimidone derivatives targeting Mycobacterium tuberculosis (Mtb). The compounds were assessed for anti-tubercular activity using the Mi...
| 發表在: | Scientific Reports |
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| Main Authors: | , , , , , |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Nature Portfolio
2025-08-01
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| 主題: | |
| 在線閱讀: | https://doi.org/10.1038/s41598-025-14734-1 |