Effects of a high-fat diet on spontaneous metastasis of Lewis lung carcinoma in plasminogen activator inhibitor-1 deficient and wild-type mice.

This study investigated the effects of a high-fat diet on spontaneous metastasis of Lewis lung carcinoma (LLC) in plasminogen activator inhibitor-1 deficient (PAI-1-/-) and wild-type mice. The high-fat diet increased the number of pulmonary metastases by 60% (p<0.01), tumor cross-sectional area b...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Lin Yan, Lana C DeMars
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Online Access:http://europepmc.org/articles/PMC4214820?pdf=render