Identification and experimental verification of necroptosis-related prognostic gene signature and characterization of tumor immune infiltration in lung squamous cell carcinoma

Background Lung squamous cell carcinoma (LUSC) is a common and aggressive malignancy. Necroptosis, a regulated mode of cell death, has been implicated in tumor immunity and oncogenic processes, yet the mechanistic involvement of necroptosis-related genes (NRGs) in LUSC pathogenesis remains unclear,...

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Bibliographic Details

Published in:	PeerJ
Main Authors:	Kai Sun, Ke-run Wang, Song Wen, Juan-juan Hong, Yu-lang Fei, Qing-hua Pan, Fang-fang Xie
Format:	Article
Language:	English
Published:	PeerJ Inc. 2025-10-01
Subjects:	Lung squamous cell carcinoma Necroptosis Prognosis signature Immunohistochemistry Tumor immune infiltration
Online Access:	https://peerj.com/articles/20260.pdf