Cell-autonomous targeting of arabinogalactan by host immune factors inhibits mycobacterial growth

Deeper understanding of the crosstalk between host cells and Mycobacterium tuberculosis (Mtb) provides crucial guidelines for the rational design of novel intervention strategies against tuberculosis (TB). Mycobacteria possess a unique complex cell wall with arabinogalactan (AG) as a critical compon...

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Bibliographic Details

Published in:	eLife
Main Authors:	Lianhua Qin, Junfang Xu, Jianxia Chen, Sen Wang, Ruijuan Zheng, Zhenling Cui, Zhonghua Liu, Xiangyang Wu, Jie Wang, Xiaochen Huang, Zhaohui Wang, Mingqiao Wang, Rong Pan, Stefan HE Kaufmann, Xun Meng, Lu Zhang, Wei Sha, Haipeng Liu
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2024-11-01
Subjects:	Mycobacterium tuberculosis tuberculosis arabinogalactan galectin-9 antibody
Online Access:	https://elifesciences.org/articles/92737