Palmitoylated antigens for the induction of anti-tumor CD8+ T cells and enhanced tumor recognition

Induction of tumor-specific cytotoxic CD8+ T cells (CTLs) via immunization relies on the presentation of tumor-associated peptides in major histocompatibility complex (MHC) class I molecules by dendritic cells (DCs). To achieve presentation of exogenous peptides into MHC class I, cytosolic processin...

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Bibliographic Details

Published in:	Molecular Therapy: Oncolytics
Main Authors:	Dorian A. Stolk, Sophie K. Horrevorts, Sjoerd T.T. Schetters, Laura J.W. Kruijssen, Sanne Duinkerken, Eelco Keuning, Martino Ambrosini, Hakan Kalay, Rieneke van de Ven, Juan J. Garcia-Vallejo, Tanja D. de Gruijl, Sandra J. van Vliet, Yvette van Kooyk
Format:	Article
Language:	English
Published:	Elsevier 2021-06-01
Subjects:	mono-palmitoylation palmitic acid peptide modification antigen dendritic cell anti-tumor
Online Access:	http://www.sciencedirect.com/science/article/pii/S2372770521000590