Synthesis, Cytotoxic and Antimalarial Activities of Benzoyl Thiosemicarbazone Analogs of Isoquinoline and Related Compounds

Thiosemicarbazone analogs of papaveraldine and related compounds 1–6 were synthesized and evaluated for cytotoxic and antimalarial activities. The cytotoxic activity was tested against HuCCA-1, HepG2, A549 and MOLT-3 human cancer cell lines. Thiosemicarbazones 1–5 displayed cytotoxicity toward all t...

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Bibliographic Details
Published in:Molecules
Main Authors: Somsak Ruchirawat, Ratchanok Pingaew, Supaluk Prachayasittikul
Format: Article
Language:English
Published: MDPI AG 2010-02-01
Subjects:
thiosemicarbazone
papaveraldine
cytotoxic activity
antimalarial activity
Online Access:http://www.mdpi.com/1420-3049/15/2/988/

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http://www.mdpi.com/1420-3049/15/2/988/

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