Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton’s jelly mesenchymal stromal cells

Abstract Background Mesenchymal stromal cells (MSCs) from various tissues have shown moderate therapeutic efficacy in reversing liver fibrosis in preclinical models. Here, we compared the relative therapeutic potential of pooled, adult human bone marrow (BM)- and neonatal Wharton’s jelly (WJ)-derive...

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Bibliographic Details

Published in:	Stem Cell Research & Therapy
Main Authors:	Mathiyazhagan Rengasamy, Gurbind Singh, Noor Atiqah Fakharuzi, Siddikuzzaman, Sudha Balasubramanian, Priyanka Swamynathan, Charan Thej, Gopinath Sasidharan, Pawan Kumar Gupta, Anjan Kumar Das, Ahmad Zuhairi Abd Rahman, Kamal Shaik Fakiruddin, Lim Moon Nian, Zubaidah Zakaria, Anish S. Majumdar
Format:	Article
Language:	English
Published:	BMC 2017-06-01
Subjects:	Human BM- and WJ-MSCs Liver fibrosis MMPs Angiogenesis
Online Access:	http://link.springer.com/article/10.1186/s13287-017-0595-1